Korean Genosys Bio-Needling with PDRN

GENOSYS Bio-Meso™ PDRN is a professional-grade skin treatment designed for repair, regeneration, and rejuvenation. Clinically proven and scientifically backed, this next-generation therapy delivers enhanced skin health, hydration, and texture improvement - all while preserving the skin barrier.

Bio-Meso™ PDRN is a safe, highly effective alternative to traditional microneedling, achieving similar results with minimal discomfort and downtime.

Discover the secret to Korean ‘Glass Skin’

Mechanism of Spicule treatment

Spicule treatment uses microscopic needle-like structures that physically penetrate the skin’s outer layer—the stratum corneum—and reach into the epidermis. Once applied through massage or stamping, these spicules:

1. Create microchannels

They form tiny, temporary channels in the skin without causing bleeding, similar to microneedling.

2. Stimulate skin renewal

The physical presence of spicules stimulates skin cell turnover, fibroblast activity, and collagen production.

3. Enhance absorption

The microchannels facilitate deep delivery of active ingredients, especially when spicules are coated with agents like PDRN, peptides, or growth factors.

4. Trigger natural exfoliation

The spicules remain in the skin for 24–72 hours, continuously stimulating the skin and resulting in natural shedding and renewal.

Effects of PDRN with spicules

The combination of PDRN (Polydeoxyribonucleotide) with spicules creates a synergistic skin treatment that enhances both regeneration and delivery.

1) Enhanced transdermal delivery

Spicules create thousands of microchannels in the skin, allowing PDRN to penetrate deeper than topical application alone. This boosts bioavailability and ensures the active ingredient reaches the dermis where it is most effective.

2) Regeneration support

PDRN promotes tissue repair, cell proliferation, and improved skin elasticity by stimulating fibroblast activity and collagen synthesis. This accelerates recovery and enhances anti-aging effects, especially after physical stimulation from the spicules.

3) Reduced downtime and inflammation

Although spicules cause mild controlled irritation for skin renewal, PDRN helps soothe inflammation, reduce redness, and promote faster healing, making the treatment more tolerable and suitable even for sensitive skin.

4) Dual-action mechanism

Spicules mechanically stimulate turnover, while PDRN biochemically supports regeneration. Together, they activate both the physical and biological pathways of skin rejuvenation. This combination is effective for skin aging, dehydration, dullness, and compromised barrier function.

What is PDRN

PDRN (60,000ppm)
Salmon-derived DNA (95% similarity to human DNA)
Promotes the release of anti-inflammatory cytokines to help soothe damaged skin.
Accelerates cell turnover for visible anti-aging effects.
Supports collagen and elastin synthesis.
Strengthens the skin barrier and protects against external aggressors.

Key Benefits

Boosts skin turnover
Enhances collagen & elastin production
Promotes skin regeneration
Improves microcirculation & oxygenation
Improves skin tone
Improves blemishes
Reduces pigmentation

Key Ingredients

Spicules per 1ml: 300,000~360,000ea
Panthenol 10,000pppm + 5 ceramides (Barrier Strengthening)
8 Anti-aging peptides (anti-Aging)
9 Growth factor peptides (Skin Revitalizing)

Contraindications

Active skin infections
Severe acne or rosacea
Open wounds or broken skin
Skin allergies or hypersensitivity
Autoimmune skin disorders
Recent dermatological procedures.
Use of retinoids or strong acids

GENOSYS Bio-Meso™ PDRN - Advanced Skin Regeneration Treatment

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